protein dephosphorylation prevents aggravated periodontitis with occlusal trauma

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eqalix

Inhibition of yes-associated protein dephosphorylation prevents aggravated periodontitis with occlusal trauma

Background: Occlusal trauma can worsen periodontitis, however the mechanism stays unclear. Sure-associated protein (YAP), a mechanical stressor protein, might play an necessary position on this course of.

Strategies: Western blot and quantitative real-time polymerase chain response (qRT-PCR) had been utilized to detect the expression of YAP and inflammatory components in sufferers with periodontitis accompanied with or with out occlusal trauma.

By way of native administration of Porphyromonas gingivalis and composite resin bonding on maxillary molars in mice, we established periodontitis and occlusal trauma fashions.

Remedy with or with out XAV939, to inhibit YAP activation, was carried out in these fashions. Micro-computed tomography, immunofluorescence (IF), and qRT-PCR had been used to discover the YAP pathway in periodontitis with occlusal trauma.

Cyclic stress and lipopolysaccharide (LPS) stimuli had been utilized to the L929 mouse fibroblast cell line with or with out XAV939. Western blot, IF, and qRT-PCR had been used to confirm the in vivo outcomes.

Outcomes: Activated dephosphorylated YAP and elevated expression of inflammatory components had been noticed in sufferers with periodontitis accompanied with occlusal trauma. Within the mouse mannequin of periodontitis with occlusal trauma, YAP transferred into the nucleus, leading to Jun N-terminal kinases (JNK) associated pro-inflammatory pathway up-regulation. L929 cell cyclic stress and LPS stimulation outcomes confirmed the in vivo outcomes. Software of XAV939 inhibited YAP protein dephosphorylation and lowered JNK pro-inflammatory pathway issue expression in vivo and in vitro.

Conclusions: Occlusal trauma can activate YAP nuclear switch, ensuing within the up-regulation of the JNK pro-inflammatory pathway. This may be inhibited by the XAV939 YAP inhibitor. This text is protected by copyright. All rights reserved..

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eqalix

Mouse Clusterin (CLU) ELISA Kit

DLR-CLU-Mu-96T 96T
EUR 487
  • Should the Mouse Clusterin (CLU) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Clusterin (CLU) in samples from serum, plasma, urine, breast milk, tissue homogenates, cell lysates, cerebrospinal fluid, cell culture supernates or other biological fluids.

Mouse Clusterin (CLU) ELISA Kit

RDR-CLU-Mu-48Tests 48 Tests
EUR 384

Mouse Clusterin (CLU) ELISA Kit

RDR-CLU-Mu-96Tests 96 Tests
EUR 527

Mouse Clusterin (CLU) ELISA Kit

RD-CLU-Mu-48Tests 48 Tests
EUR 368

Mouse Clusterin (CLU) ELISA Kit

RD-CLU-Mu-96Tests 96 Tests
EUR 504

Canine Clusterin (CLU) ELISA Kit

DLR-CLU-c-48T 48T
EUR 549
  • Should the Canine Clusterin (CLU) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Canine Clusterin (CLU) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Clusterin (CLU) ELISA Kit

DLR-CLU-c-96T 96T
EUR 718
  • Should the Canine Clusterin (CLU) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Canine Clusterin (CLU) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Clusterin (CLU) ELISA Kit

DLR-CLU-Hu-48T 48T
EUR 392
  • Should the Human Clusterin (CLU) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Clusterin (CLU) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Clusterin (CLU) ELISA Kit

DLR-CLU-Hu-96T 96T
EUR 502
  • Should the Human Clusterin (CLU) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Clusterin (CLU) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Clusterin (CLU) ELISA Kit

DLR-CLU-Ra-48T 48T
EUR 528
  • Should the Rat Clusterin (CLU) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Clusterin (CLU) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Clusterin (CLU) ELISA Kit

DLR-CLU-Ra-96T 96T
EUR 690
  • Should the Rat Clusterin (CLU) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Clusterin (CLU) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Clusterin (CLU) ELISA Kit

RDR-CLU-c-48Tests 48 Tests
EUR 583

Canine Clusterin (CLU) ELISA Kit

RDR-CLU-c-96Tests 96 Tests
EUR 811

Human Clusterin (CLU) ELISA Kit

RDR-CLU-Hu-48Tests 48 Tests
EUR 396

Human Clusterin (CLU) ELISA Kit

RDR-CLU-Hu-96Tests 96 Tests
EUR 545

Rat Clusterin (CLU) ELISA Kit

RDR-CLU-Ra-48Tests 48 Tests
EUR 558

Rat Clusterin (CLU) ELISA Kit

RDR-CLU-Ra-96Tests 96 Tests
EUR 776

Canine Clusterin (CLU) ELISA Kit

RD-CLU-c-48Tests 48 Tests
EUR 557

Canine Clusterin (CLU) ELISA Kit

RD-CLU-c-96Tests 96 Tests
EUR 775

Human Clusterin (CLU) ELISA Kit

RD-CLU-Hu-48Tests 48 Tests
EUR 380

Human Clusterin (CLU) ELISA Kit

RD-CLU-Hu-96Tests 96 Tests
EUR 521

Rat Clusterin (CLU) ELISA Kit

RD-CLU-Ra-48Tests 48 Tests
EUR 534

Rat Clusterin (CLU) ELISA Kit

RD-CLU-Ra-96Tests 96 Tests
EUR 742

Clusterin (CLU) Monoclonal Antibody (Pig)

4-MAB180Po21
  • EUR 276.00
  • EUR 2972.00
  • EUR 730.00
  • EUR 352.00
  • EUR 226.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ile229~Glu446
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Pig Clusterin (CLU)

Clusterin (CLU) Monoclonal Antibody (Rat)

4-MAB180Ra21
  • EUR 260.00
  • EUR 2721.00
  • EUR 673.00
  • EUR 329.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser227~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Clusterin (CLU)

Clusterin (CLU) Monoclonal Antibody (Rabbit)

4-MAB180Rb21
  • EUR 260.00
  • EUR 2721.00
  • EUR 673.00
  • EUR 329.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Asn226~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rabbit Clusterin (CLU)

Clusterin (CLU) Antibody

20-abx111697
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

20-abx130424
  • EUR 481.00
  • EUR 133.00
  • EUR 1442.00
  • EUR 676.00
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Antibody

20-abx109653
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

20-abx001253
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

20-abx137211
  • EUR 704.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 20 ug
  • 5 ug
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

abx139360-01mg 0.1 mg
EUR 398
  • Shipped within 5-12 working days.

Clusterin (CLU) Antibody

abx036348-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

abx036349-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

20-abx104829
  • EUR 467.00
  • EUR 133.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Antibody

20-abx100235
  • EUR 314.00
  • EUR 133.00
  • EUR 829.00
  • EUR 439.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Antibody

20-abx100236
  • EUR 314.00
  • EUR 133.00
  • EUR 857.00
  • EUR 439.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Antibody

20-abx100237
  • EUR 300.00
  • EUR 704.00
  • EUR 356.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Antibody

20-abx100238
  • EUR 439.00
  • EUR 133.00
  • EUR 1247.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Clusterin (CLU) Antibody

20-abx100239
  • EUR 439.00
  • EUR 133.00
  • EUR 1247.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Clusterin (CLU) Antibody

20-abx100240
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Clusterin (CLU) Antibody

20-abx100241
  • EUR 342.00
  • EUR 871.00
  • EUR 453.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Antibody

20-abx100242
  • EUR 342.00
  • EUR 871.00
  • EUR 453.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Antibody

20-abx100243
  • EUR 467.00
  • EUR 133.00
  • EUR 1358.00
  • EUR 648.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Antibody

abx026000-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

abx026000-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

abx018139-100ug 100 ug
EUR 384
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

20-abx175911
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.

Clusterin (CLU) Antibody

20-abx329365
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

abx430866-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Clusterin (CLU) Antibody

abx430867-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Clusterin (CLU) Antibody

abx430877-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Clusterin (CLU) Antibody

abx430878-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Clusterin (CLU) Antibody

20-abx225116
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

abx231781-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Clusterin (CLU) Antibody

abx231782-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Clusterin (CLU) Antibody

20-abx210640
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody

20-abx171801
  • EUR 356.00
  • EUR 940.00
  • EUR 481.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Monoclonal Antibody (Human, Pig)

4-MAB180Hu22
  • EUR 221.00
  • EUR 2114.00
  • EUR 535.00
  • EUR 274.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser228~Glu449
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Human, Pig Clusterin (CLU)

Clusterin (CLU) Monoclonal Antibody (Pig), APC

4-MAB180Po21-APC
  • EUR 389.00
  • EUR 3905.00
  • EUR 1070.00
  • EUR 503.00
  • EUR 238.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ile229~Glu446
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Pig Clusterin (CLU). This antibody is labeled with APC.

Clusterin (CLU) Monoclonal Antibody (Pig), Biotinylated

4-MAB180Po21-Biotin
  • EUR 344.00
  • EUR 2922.00
  • EUR 843.00
  • EUR 427.00
  • EUR 233.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ile229~Glu446
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Pig Clusterin (CLU). This antibody is labeled with Biotin.

Clusterin (CLU) Monoclonal Antibody (Pig), Cy3

4-MAB180Po21-Cy3
  • EUR 477.00
  • EUR 5165.00
  • EUR 1385.00
  • EUR 629.00
  • EUR 276.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ile229~Glu446
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Pig Clusterin (CLU). This antibody is labeled with Cy3.

Clusterin (CLU) Monoclonal Antibody (Pig), FITC

4-MAB180Po21-FITC
  • EUR 331.00
  • EUR 3144.00
  • EUR 876.00
  • EUR 422.00
  • EUR 210.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ile229~Glu446
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Pig Clusterin (CLU). This antibody is labeled with FITC.

Clusterin (CLU) Monoclonal Antibody (Pig), HRP

4-MAB180Po21-HRP
  • EUR 354.00
  • EUR 3401.00
  • EUR 944.00
  • EUR 452.00
  • EUR 223.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ile229~Glu446
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Pig Clusterin (CLU). This antibody is labeled with HRP.

Clusterin (CLU) Monoclonal Antibody (Pig), PE

4-MAB180Po21-PE
  • EUR 331.00
  • EUR 3144.00
  • EUR 876.00
  • EUR 422.00
  • EUR 210.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ile229~Glu446
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Pig Clusterin (CLU). This antibody is labeled with PE.

Clusterin (CLU) Monoclonal Antibody (Rat), APC

4-MAB180Ra21-APC
  • EUR 365.00
  • EUR 3563.00
  • EUR 984.00
  • EUR 468.00
  • EUR 228.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser227~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Clusterin (CLU). This antibody is labeled with APC.

Clusterin (CLU) Monoclonal Antibody (Rat), Biotinylated

4-MAB180Ra21-Biotin
  • EUR 326.00
  • EUR 2671.00
  • EUR 780.00
  • EUR 402.00
  • EUR 225.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser227~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Clusterin (CLU). This antibody is labeled with Biotin.

Clusterin (CLU) Monoclonal Antibody (Rat), Cy3

4-MAB180Ra21-Cy3
  • EUR 445.00
  • EUR 4709.00
  • EUR 1271.00
  • EUR 583.00
  • EUR 263.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser227~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Clusterin (CLU). This antibody is labeled with Cy3.

Clusterin (CLU) Monoclonal Antibody (Rat), FITC

4-MAB180Ra21-FITC
  • EUR 312.00
  • EUR 2870.00
  • EUR 807.00
  • EUR 395.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser227~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Clusterin (CLU). This antibody is labeled with FITC.

Clusterin (CLU) Monoclonal Antibody (Rat), HRP

4-MAB180Ra21-HRP
  • EUR 333.00
  • EUR 3104.00
  • EUR 869.00
  • EUR 422.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser227~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Clusterin (CLU). This antibody is labeled with HRP.

Clusterin (CLU) Monoclonal Antibody (Rat), PE

4-MAB180Ra21-PE
  • EUR 312.00
  • EUR 2870.00
  • EUR 807.00
  • EUR 395.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser227~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Clusterin (CLU). This antibody is labeled with PE.

Clusterin (CLU) Monoclonal Antibody (Rabbit), APC

4-MAB180Rb21-APC
  • EUR 365.00
  • EUR 3563.00
  • EUR 984.00
  • EUR 468.00
  • EUR 228.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Asn226~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rabbit Clusterin (CLU). This antibody is labeled with APC.

Clusterin (CLU) Monoclonal Antibody (Rabbit), Biotinylated

4-MAB180Rb21-Biotin
  • EUR 326.00
  • EUR 2671.00
  • EUR 780.00
  • EUR 402.00
  • EUR 225.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Asn226~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rabbit Clusterin (CLU). This antibody is labeled with Biotin.

Clusterin (CLU) Monoclonal Antibody (Rabbit), Cy3

4-MAB180Rb21-Cy3
  • EUR 445.00
  • EUR 4709.00
  • EUR 1271.00
  • EUR 583.00
  • EUR 263.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Asn226~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rabbit Clusterin (CLU). This antibody is labeled with Cy3.

Clusterin (CLU) Monoclonal Antibody (Rabbit), FITC

4-MAB180Rb21-FITC
  • EUR 312.00
  • EUR 2870.00
  • EUR 807.00
  • EUR 395.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Asn226~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rabbit Clusterin (CLU). This antibody is labeled with FITC.

Clusterin (CLU) Monoclonal Antibody (Rabbit), HRP

4-MAB180Rb21-HRP
  • EUR 333.00
  • EUR 3104.00
  • EUR 869.00
  • EUR 422.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Asn226~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rabbit Clusterin (CLU). This antibody is labeled with HRP.

Clusterin (CLU) Monoclonal Antibody (Rabbit), PE

4-MAB180Rb21-PE
  • EUR 312.00
  • EUR 2870.00
  • EUR 807.00
  • EUR 395.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Asn226~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rabbit Clusterin (CLU). This antibody is labeled with PE.

Clusterin (CLU) Polyclonal Antibody (Mouse)

4-PAB180Mu01
  • EUR 194.00
  • EUR 1678.00
  • EUR 436.00
  • EUR 234.00
  • EUR 191.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Clusterin (CLU)

Mouse Clusterin (CLU) Protein

20-abx065949
  • EUR 578.00
  • EUR 258.00
  • EUR 1678.00
  • EUR 676.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Monoclonal Antibody (Human, Pig), APC

4-MAB180Hu22-APC
  • EUR 307.00
  • EUR 2735.00
  • EUR 777.00
  • EUR 386.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser228~Glu449
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Human, Pig Clusterin (CLU). This antibody is labeled with APC.

Clusterin (CLU) Monoclonal Antibody (Human, Pig), Biotinylated

4-MAB180Hu22-Biotin
  • EUR 283.00
  • EUR 2064.00
  • EUR 628.00
  • EUR 341.00
  • EUR 207.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser228~Glu449
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Human, Pig Clusterin (CLU). This antibody is labeled with Biotin.

Clusterin (CLU) Monoclonal Antibody (Human, Pig), Cy3

4-MAB180Hu22-Cy3
  • EUR 368.00
  • EUR 3605.00
  • EUR 995.00
  • EUR 473.00
  • EUR 229.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser228~Glu449
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Human, Pig Clusterin (CLU). This antibody is labeled with Cy3.

Clusterin (CLU) Monoclonal Antibody (Human, Pig), FITC

4-MAB180Hu22-FITC
  • EUR 266.00
  • EUR 2208.00
  • EUR 642.00
  • EUR 328.00
  • EUR 182.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser228~Glu449
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Human, Pig Clusterin (CLU). This antibody is labeled with FITC.

Clusterin (CLU) Monoclonal Antibody (Human, Pig), HRP

4-MAB180Hu22-HRP
  • EUR 283.00
  • EUR 2387.00
  • EUR 690.00
  • EUR 351.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser228~Glu449
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Human, Pig Clusterin (CLU). This antibody is labeled with HRP.

Clusterin (CLU) Monoclonal Antibody (Human, Pig), PE

4-MAB180Hu22-PE
  • EUR 266.00
  • EUR 2208.00
  • EUR 642.00
  • EUR 328.00
  • EUR 182.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser228~Glu449
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Human, Pig Clusterin (CLU). This antibody is labeled with PE.

Clusterin (CLU) Monoclonal Antibody (Pig), APC-Cy7

4-MAB180Po21-APC-Cy7
  • EUR 659.00
  • EUR 7690.00
  • EUR 2020.00
  • EUR 886.00
  • EUR 356.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ile229~Glu446
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Pig Clusterin (CLU). This antibody is labeled with APC-Cy7.

Clusterin (CLU) Monoclonal Antibody (Rat), APC-Cy7

4-MAB180Ra21-APC-Cy7
  • EUR 610.00
  • EUR 7006.00
  • EUR 1849.00
  • EUR 817.00
  • EUR 337.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser227~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Clusterin (CLU). This antibody is labeled with APC-Cy7.

Clusterin (CLU) Monoclonal Antibody (Rabbit), APC-Cy7

4-MAB180Rb21-APC-Cy7
  • EUR 610.00
  • EUR 7006.00
  • EUR 1849.00
  • EUR 817.00
  • EUR 337.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Asn226~Glu447
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rabbit Clusterin (CLU). This antibody is labeled with APC-Cy7.

Clusterin (CLU) Antibody Pair

abx117479-1pair5x96wellplates 1 pair (5x96 well plates)
EUR 1010
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody (Biotin)

20-abx105267
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody (FITC)

20-abx106686
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody (HRP)

20-abx108103
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Clusterin (CLU) Antibody (Biotin)

20-abx273476
  • EUR 509.00
  • EUR 258.00
  • EUR 1539.00
  • EUR 718.00
  • EUR 411.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (FITC)

20-abx273520
  • EUR 509.00
  • EUR 258.00
  • EUR 1525.00
  • EUR 704.00
  • EUR 411.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (FITC)

20-abx273718
  • EUR 356.00
  • EUR 217.00
  • EUR 996.00
  • EUR 495.00
  • EUR 300.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (FITC)

20-abx273946
  • EUR 342.00
  • EUR 217.00
  • EUR 968.00
  • EUR 481.00
  • EUR 286.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (FITC)

20-abx274058
  • EUR 509.00
  • EUR 258.00
  • EUR 1525.00
  • EUR 704.00
  • EUR 411.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (FITC)

20-abx274096
  • EUR 495.00
  • EUR 258.00
  • EUR 1455.00
  • EUR 690.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody Pair

20-abx370043
  • EUR 1790.00
  • EUR 1149.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody Pair

20-abx370044
  • EUR 1288.00
  • EUR 843.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody Pair

20-abx370079
  • EUR 1288.00
  • EUR 843.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody Pair

20-abx370716
  • EUR 1776.00
  • EUR 1135.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody Pair

20-abx370717
  • EUR 1706.00
  • EUR 1094.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody Pair

20-abx370756
  • EUR 1873.00
  • EUR 1191.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (Biotin)

20-abx271664
  • EUR 481.00
  • EUR 244.00
  • EUR 1414.00
  • EUR 662.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (Biotin)

20-abx272100
  • EUR 342.00
  • EUR 217.00
  • EUR 940.00
  • EUR 481.00
  • EUR 286.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (Biotin)

20-abx272772
  • EUR 328.00
  • EUR 217.00
  • EUR 899.00
  • EUR 453.00
  • EUR 286.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (Biotin)

20-abx273040
  • EUR 481.00
  • EUR 244.00
  • EUR 1414.00
  • EUR 662.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Clusterin (CLU) Antibody (Biotin)

20-abx273237
  • EUR 467.00
  • EUR 244.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Human Clusterin (CLU)

1-CSB-RP060294h
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 27.8 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Clusterin(CLU) ,partial expressed in E.coli

Human Clusterin (CLU)

1-CSB-EP005595HU
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 70.1 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Clusterin(CLU) expressed in E.coli

Recombinant Clusterin (CLU)

4-RPB180Bo01
  • EUR 512.16
  • EUR 240.00
  • EUR 1645.60
  • EUR 615.20
  • EUR 1130.40
  • EUR 406.00
  • EUR 3964.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P17697
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 28.8kDa
  • Isoelectric Point: 6.4
Description: Recombinant Bovine Clusterin expressed in: E.coli

Recombinant Clusterin (CLU)

4-RPB180Ca01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P25473
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 31.0kDa
  • Isoelectric Point: 5.5
Description: Recombinant Dog Clusterin expressed in: E.coli

Recombinant Clusterin (CLU)

4-RPB180Hu01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P10909
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 27.1kDa
  • Isoelectric Point: 6.1
Description: Recombinant Human Clusterin expressed in: E.coli

Recombinant Clusterin (CLU)

4-RPB180Mu01
  • EUR 404.64
  • EUR 211.00
  • EUR 1242.40
  • EUR 480.80
  • EUR 861.60
  • EUR 334.00
  • EUR 2956.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q06890
  • Buffer composition: 100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 26.7kDa
  • Isoelectric Point: 5.4
Description: Recombinant Mouse Clusterin expressed in: E.coli

Recombinant Clusterin (CLU)

4-RPB180Ov01
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: W5PZI0
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 52.6kDa
  • Isoelectric Point: Inquire
Description: Recombinant Sheep Clusterin expressed in: E.coli

Recombinant Clusterin (CLU)

4-RPB180Po01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q29549
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 26.6kDa
  • Isoelectric Point: 6
Description: Recombinant Pig Clusterin expressed in: E.coli

Recombinant Clusterin (CLU)

4-RPB180Ra01
  • EUR 440.48
  • EUR 221.00
  • EUR 1376.80
  • EUR 525.60
  • EUR 951.20
  • EUR 358.00
  • EUR 3292.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P05371
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 26.7kDa
  • Isoelectric Point: 5.3
Description: Recombinant Rat Clusterin expressed in: E.coli

Recombinant Clusterin (CLU)

4-RPB180Rb01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q9XSC5
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 27.1kDa
  • Isoelectric Point: 5.6
Description: Recombinant Rabbit Clusterin expressed in: E.coli

Clusterin (CLU) Polyclonal Antibody (Mouse), APC

4-PAB180Mu01-APC
  • EUR 266.00
  • EUR 2141.00
  • EUR 629.00
  • EUR 326.00
  • EUR 185.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Clusterin (CLU). This antibody is labeled with APC.

Clusterin (CLU) Polyclonal Antibody (Mouse), Biotinylated

4-PAB180Mu01-Biotin
  • EUR 253.00
  • EUR 1628.00
  • EUR 519.00
  • EUR 297.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Clusterin (CLU). This antibody is labeled with Biotin.

Clusterin (CLU) Polyclonal Antibody (Mouse), Cy3

4-PAB180Mu01-Cy3
  • EUR 313.00
  • EUR 2813.00
  • EUR 797.00
  • EUR 393.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Clusterin (CLU). This antibody is labeled with Cy3.

Clusterin (CLU) Polyclonal Antibody (Mouse), FITC

4-PAB180Mu01-FITC
  • EUR 233.00
  • EUR 1732.00
  • EUR 523.00
  • EUR 281.00
  • EUR 168.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Clusterin (CLU). This antibody is labeled with FITC.

Clusterin (CLU) Polyclonal Antibody (Mouse), HRP

4-PAB180Mu01-HRP
  • EUR 247.00
  • EUR 1872.00
  • EUR 561.00
  • EUR 299.00
  • EUR 177.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Clusterin (CLU). This antibody is labeled with HRP.

Clusterin (CLU) Polyclonal Antibody (Mouse), PE

4-PAB180Mu01-PE
  • EUR 233.00
  • EUR 1732.00
  • EUR 523.00
  • EUR 281.00
  • EUR 168.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Clusterin (CLU). This antibody is labeled with PE.

Clusterin (CLU) Polyclonal Antibody (Mouse, Rat)

4-PAB180Ra01
  • EUR 251.00
  • EUR 2589.00
  • EUR 643.00
  • EUR 317.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Clusterin (CLU)

Mouse Clusterin (CLU) ELISA Kit

abx575060-96tests 96 tests
EUR 637
  • Shipped within 5-12 working days.

Mouse Clu/ Clusterin ELISA Kit

E1626Mo 1 Kit
EUR 546

Mouse Clusterin, Clu ELISA KIT

ELI-03898m 96 Tests
EUR 865

Mouse CLU(Clusterin) ELISA Kit

EM0058 96T
EUR 524.1
  • Detection range: 2.5-160 ng/ml
  • Uniprot ID: Q06890
  • Alias: CLU/Clusterin/CLU/APO-J/APOJ/CLI/KUB1/NA1/NA2/SGP2/SP-40/TRPM2
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 1.5 ng/ml

Mouse Clusterin (CLU) ELISA Kit

20-abx153835
  • EUR 5640.00
  • EUR 3009.00
  • EUR 707.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Mouse Clusterin (CLU) CLIA Kit

abx195172-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Mouse Clusterin (CLU) CLIA Kit

20-abx492471
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Mouse Clusterin (CLU) ELISA Kit

abx254011-96tests 96 tests
EUR 637
  • Shipped within 5-12 working days.

Mouse Clusterin(CLU) ELISA kit

CSB-EL005595MO-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitative sandwich ELISA kit for measuring Mouse Clusterin (CLU) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Clusterin(CLU) ELISA kit

1-CSB-EL005595MO
  • EUR 602.00
  • EUR 4238.00
  • EUR 2256.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitative sandwich ELISA kit for measuring Mouse Clusterin(CLU) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Clusterin (CLU) ELISA Kit

SEB180Mu-10x96wellstestplate 10x96-wells test plate
EUR 3409.41
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Clusterin (CLU) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Clusterin (CLU) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Clusterin (CLU) ELISA Kit

SEB180Mu-1x48wellstestplate 1x48-wells test plate
EUR 368.42
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Clusterin (CLU) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Clusterin (CLU) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Clusterin (CLU) ELISA Kit

SEB180Mu-1x96wellstestplate 1x96-wells test plate
EUR 483.46
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Clusterin (CLU) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Clusterin (CLU) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Clusterin (CLU) ELISA Kit

SEB180Mu-5x96wellstestplate 5x96-wells test plate
EUR 1875.57
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Clusterin (CLU) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Clusterin (CLU) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Clusterin (CLU) ELISA Kit

4-SEB180Mu
  • EUR 3460.00
  • EUR 1826.00
  • EUR 484.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Clusterin elisa. Alternative names of the recognized antigen: CLU
  • TRPM2
  • KUB1
  • CLI
  • APOJ
  • SGP2
  • AAG4
  • APO-J
  • SP-40
  • Apolipoprotein J
  • Complement Lysis Inhibitor
  • 40, Sulfated Glycoprotein 2
  • Testosterone-Repressed Prostate Message 2
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Clusterin (CLU) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Clusterin ELISA Kit (CLU)

RK02691 96 Tests
EUR 521

Mouse Clusterin(CLU)ELISA Kit

QY-E20343 96T
EUR 361

Clusterin (CLU) Monoclonal Antibody (Human, Pig), APC-Cy7

4-MAB180Hu22-APC-Cy7
  • EUR 495.00
  • EUR 5350.00
  • EUR 1435.00
  • EUR 652.00
  • EUR 286.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser228~Glu449
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Human, Pig Clusterin (CLU). This antibody is labeled with APC-Cy7.

Clusterin (CLU) Polyclonal Antibody (Bovine)

4-PAB180Bo01
  • EUR 267.00
  • EUR 2826.00
  • EUR 697.00
  • EUR 338.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Val223~Glu439)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Clusterin (CLU)

Clusterin (CLU) Polyclonal Antibody (Dog)

4-PAB180Ca01
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Asn227~Glu445)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Dog Clusterin (CLU)

Clusterin (CLU) Polyclonal Antibody (Human)

4-PAB180Hu01
  • EUR 198.00
  • EUR 1744.00
  • EUR 451.00
  • EUR 240.00
  • EUR 193.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser228~Glu449)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Clusterin (CLU)

Clusterin (CLU) Polyclonal Antibody (Goat)

4-PAB180Ov01
  • EUR 280.00
  • EUR 3024.00
  • EUR 742.00
  • EUR 356.00
  • EUR 227.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ile20~Glu439)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Goat Clusterin (CLU)

Clusterin (CLU) Polyclonal Antibody (Pig)

4-PAB180Po01
  • EUR 268.00
  • EUR 2840.00
  • EUR 700.00
  • EUR 340.00
  • EUR 223.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ile229~Glu446)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pig Clusterin (CLU)

Dog Clusterin (CLU) Protein

20-abx065947
  • EUR 662.00
  • EUR 272.00
  • EUR 2040.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Human Clusterin (CLU) Protein

20-abx065948
  • EUR 648.00
  • EUR 272.00
  • EUR 1943.00
  • EUR 759.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Rat Clusterin (CLU) Protein

20-abx065950
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Rabbit Clusterin (CLU) Protein

20-abx065951
  • EUR 662.00
  • EUR 272.00
  • EUR 2040.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Pig Clusterin (CLU) Protein

20-abx065952
  • EUR 662.00
  • EUR 272.00
  • EUR 2040.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Sheep Clusterin (CLU) Protein

20-abx167805
  • EUR 732.00
  • EUR 286.00
  • EUR 2305.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Cow Clusterin (CLU) Protein

20-abx168004
  • EUR 718.00
  • EUR 286.00
  • EUR 2221.00
  • EUR 857.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Clusterin (CLU) Polyclonal Antibody (Mouse), APC-Cy7

4-PAB180Mu01-APC-Cy7
  • EUR 412.00
  • EUR 4162.00
  • EUR 1138.00
  • EUR 533.00
  • EUR 250.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Clusterin (CLU). This antibody is labeled with APC-Cy7.

Clusterin (CLU) Polyclonal Antibody (Mouse, Rat), APC

4-PAB180Ra01-APC
  • EUR 352.00
  • EUR 3383.00
  • EUR 939.00
  • EUR 450.00
  • EUR 223.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Clusterin (CLU). This antibody is labeled with APC.

Clusterin (CLU) Polyclonal Antibody (Mouse, Rat), Biotinylated

4-PAB180Ra01-Biotin
  • EUR 316.00
  • EUR 2539.00
  • EUR 747.00
  • EUR 388.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Clusterin (CLU). This antibody is labeled with Biotin.

Clusterin (CLU) Polyclonal Antibody (Mouse, Rat), Cy3

4-PAB180Ra01-Cy3
  • EUR 428.00
  • EUR 4469.00
  • EUR 1211.00
  • EUR 559.00
  • EUR 255.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Clusterin (CLU). This antibody is labeled with Cy3.

Clusterin (CLU) Polyclonal Antibody (Mouse, Rat), FITC

4-PAB180Ra01-FITC
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Clusterin (CLU). This antibody is labeled with FITC.

Clusterin (CLU) Polyclonal Antibody (Mouse, Rat), HRP

4-PAB180Ra01-HRP
  • EUR 322.00
  • EUR 2948.00
  • EUR 830.00
  • EUR 407.00
  • EUR 210.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Clusterin (CLU). This antibody is labeled with HRP.

Clusterin (CLU) Polyclonal Antibody (Mouse, Rat), PE

4-PAB180Ra01-PE
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Ser227~Glu447)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Clusterin (CLU). This antibody is labeled with PE.

Mouse Anti Human Clusterin Monoclonal Antibody

CABT-47935MH 0.1 mg
EUR 944

ELISA kit for Mouse CLU (Clusterin)

E-EL-M0303 1 plate of 96 wells
EUR 534
  • Gentaur's CLU ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse CLU. Standards or samples are added to the micro ELISA plate wells and combined with the
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Mouse CLU (Clusterin) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Mouse Clusterin (CLU)

EK0323 96 tests
EUR 712
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Clusterin (CLU) in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Mouse CLU (Clusterin)

ELK1310 1 plate of 96 wells
EUR 372
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Clusterin (CLU). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Clusterin (CLU). N
  • Show more
Description: A sandwich ELISA kit for detection of Clusterin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

CLIA kit for Mouse CLU (Clusterin)

E-CL-M0202 1 plate of 96 wells
EUR 584
  • Gentaur's CLU CLIA kit utilizes the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Mouse CLU . Standards or samples are added to the micro CLIA plate wells and combined with the sp
  • Show more
Description: A sandwich CLIA kit for quantitative measurement of Mouse CLU (Clusterin) in samples from Serum, Plasma, Cell supernatant

Polyclonal CLU / Clusterin Antibody (C-Terminus)

APG02669G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human CLU / Clusterin (C-Terminus). This antibody is tested and proven to work in the following applications:

Clusterin (CLU) Polyclonal Antibody (Bovine), APC

4-PAB180Bo01-APC
  • EUR 376.00
  • EUR 3707.00
  • EUR 1020.00
  • EUR 483.00
  • EUR 232.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Val223~Glu439)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Clusterin (CLU). This antibody is labeled with APC.

Clusterin (CLU) Polyclonal Antibody (Bovine), Biotinylated

4-PAB180Bo01-Biotin
  • EUR 334.00
  • EUR 2776.00
  • EUR 806.00
  • EUR 412.00
  • EUR 228.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Val223~Glu439)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Clusterin (CLU). This antibody is labeled with Biotin.

Clusterin (CLU) Polyclonal Antibody (Bovine), Cy3

4-PAB180Bo01-Cy3
  • EUR 459.00
  • EUR 4901.00
  • EUR 1319.00
  • EUR 602.00
  • EUR 267.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Val223~Glu439)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Clusterin (CLU). This antibody is labeled with Cy3.

Clusterin (CLU) Polyclonal Antibody (Bovine), FITC

4-PAB180Bo01-FITC
  • EUR 320.00
  • EUR 2985.00
  • EUR 836.00
  • EUR 406.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Val223~Glu439)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Clusterin (CLU). This antibody is labeled with FITC.

Clusterin (CLU) Polyclonal Antibody (Bovine), HRP

4-PAB180Bo01-HRP
  • EUR 342.00
  • EUR 3229.00
  • EUR 901.00
  • EUR 435.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Val223~Glu439)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Clusterin (CLU). This antibody is labeled with HRP.

Clusterin (CLU) Polyclonal Antibody (Bovine), PE

4-PAB180Bo01-PE
  • EUR 320.00
  • EUR 2985.00
  • EUR 836.00
  • EUR 406.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CLU (Val223~Glu439)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Clusterin (CLU). This antibody is labeled with PE.

Evolutionary dynamics of SARS-CoV-2 nucleocapsid (N) protein and its penalties

  • The rising novel coronavirus SARS-CoV-2 has created a worldwide well being disaster that warrants an correct and detailed characterization of the quickly evolving viral genome for understanding its epidemiology, pathogenesis and containment.
  • Right here, we explored 61,485 sequences of the nucleocapsid (N) protein, a potent diagnostic and prophylactic goal, for figuring out the mutations to assessment their roles in real-timePCR primarily based analysis and observe consequent impacts.
  • In comparison with the Wuhan reference pressure, a complete of 1034 distinctive nucleotide mutations had been recognized within the mutant strains (49.15%, n=30,221) globally. Of those mutations, 367 occupy primer binding websites together with 3′-end mismatch to primer-pair of 11 nicely characterised primer units.
  • Noteworthy, CDC (USA) beneficial N2 primer set contained decrease mismatch than the opposite primer units. Furthermore, 684 amino acid (aa) substitutions situated throughout 317 (75.66% of whole aa) distinctive positions together with 82, 21, and 83 of these in RNA binding N-terminal area (NTD), SR-rich area, and C-terminal dimerization area (CTD), respectively.
  • Furthermore, 11 in-frame deletions, largely (n =10) inside the extremely versatile linker area, had been revealed and the remaining inside the NTD area. Moreover, we predicted the potential consequence of high-frequency mutations (≥ 20) and deletions on the tertiary construction of the N protein.
  • Remarkably, we noticed that prime frequency (67.94% of mutated sequences) co-occuring mutations (R203Ok and G204R) destabilized and decreased total structural flexibility.
  • The N protein of SARS-CoV-2 contains a median of 1.2 mutations per pressure in comparison with 4.Four and 0.Four in MERS-CoV and SARS-CoV, respectively. Regardless of being proposed because the alternate goal to spike protein for vaccine and therapeutics, ongoing evolution of the N protein might problem the endeavors, thus want additional immunoinformatics analyses.
  • Due to this fact, steady monitoring is required for tracing the continued evolution of the SARS-CoV-2 N protein in prophylactic and diagnostic interventions. This text is protected by copyright. All rights reserved.

Impairment of cell adhesion and migration by inhibition of protein disulphide isomerases in three breast most cancers cell traces

  • Protein disulphide isomerase A3 (PDIA3) is an endoplasmic reticulum (ER)-resident disulphide isomerase and oxidoreductase with recognized substrates that embrace some extracellular matrix (ECM) proteins.
  • PDIA3 is up-regulated in invasive breast cancers and correlates in a mouse orthotopic xenograft mannequin with breast most cancers metastasis to bone. Nevertheless, the underlying mobile mechanisms stay unclear.
  • Right here we investigated the perform of protein disulphide isomerases in attachment, spreading and migration of three human breast most cancers traces consultant of luminal (MCF-7) or basal (MDA-MB-231 and HCC1937) tumour phenotypes.
  • Pharmacological inhibition by 16F16 decreased preliminary cell spreading extra successfully than inhibition by PACMA-31. Cells displayed diminished cortical F-actin projections, stress fibres and focal adhesions. Cell migration was lowered in a quantified ‘scratch wound’ assay.
  • To look at whether or not these results would possibly outcome from alterations to secreted proteins within the absence of purposeful PDIA3, adhesion and migration had been quantified within the above cells uncovered to media conditioned by wildtype (WT) or Pdia3-/- mouse embryonic fibroblasts (MEFs).
  • The conditioned medium (CM) of Pdia3-/- MEFs was much less efficient in selling cell spreading and F-actin organisation or supporting ‘scratch wound’ closure.
  • Equally, ECM ready from HCC1937 cells after 16F16 inhibition was much less efficient than management ECM to assist spreading of untreated HCC1937 cells. General, these outcomes advance the idea that protein disulphide isomerases together with PDIA3 drive the manufacturing of secreted proteins that promote a microenvironment beneficial to breast most cancers cell adhesion and motility, traits which might be integral to tumour invasion and metastasis. Inhibition of PDIA3 or associated isomerases might have potential for anti-metastatic therapies.

Host Plant Methods to Fight In opposition to Viruses Effector Proteins

Viruses are obligate parasites that exist in an inactive state till they enter the host physique. Upon entry, viruses change into energetic and begin replicating by utilizing the host cell equipment. All plant viruses can increase their transmission, thus powering their detrimental results on the host plant.

To decrease an infection and illnesses brought on by viruses, the plant has a defence mechanism often known as pathogenesis-related biochemicals, that are metabolites and proteins. Proteins that in the end forestall pathogenic illnesses are referred to as R proteins.

A number of plant R genes (that verify resistance) and avirulence protein (Avr) (pathogen Avr gene-encoded proteins [effector/elicitor proteins involved in pathogenicity]) molecules have been recognized.

The popularity of such an element ends in the plant defence mechanism. Throughout plant viral an infection, the replication and expression of a viral molecule result in a sequence of a hypersensitive response (HR) and have an effect on the host plant’s immunity (pathogen-associated molecular pattern-triggered immunity and effector-triggered immunity).

Avr protein renders the host RNA silencing mechanism and its innate immunity, mainly often known as silencing suppressors in direction of the plant defensive equipment. It is a sturdy reply to the plant defensive equipment by dangerous plant viruses.

On this assessment, we describe the plant pathogen resistance protein and the way these proteins regulate host immunity throughout plant-virus interactions. Moreover, we now have mentioned concerning ribosome-inactivating proteins, ubiquitin proteasome system, translation repression (nuclear shuttle protein interacting kinase 1), DNA methylation, dominant resistance genes, and autophagy-mediated protein degradation, that are essential in antiviral defences.

Mouse Protectin (CD59) ELISA Kit

DLR-CD59-Mu-96T 96T
EUR 661
  • Should the Mouse Protectin (CD59) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Protectin (CD59) in samples from serum, plasma, urine or other biological fluids.

Mouse Protectin (CD59) ELISA Kit

RD-CD59-Mu-48Tests 48 Tests
EUR 511

Mouse Protectin (CD59) ELISA Kit

RD-CD59-Mu-96Tests 96 Tests
EUR 709

Mouse Protectin (CD59) ELISA Kit

RDR-CD59-Mu-48Tests 48 Tests
EUR 534

Mouse Protectin (CD59) ELISA Kit

RDR-CD59-Mu-96Tests 96 Tests
EUR 742

Human Protectin (CD59) ELISA Kit

DLR-CD59-Hu-48T 48T
EUR 498
  • Should the Human Protectin (CD59) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Protectin (CD59) in samples from serum, plasma, cell lysates or other biological fluids.

Human Protectin (CD59) ELISA Kit

DLR-CD59-Hu-96T 96T
EUR 647
  • Should the Human Protectin (CD59) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Protectin (CD59) in samples from serum, plasma, cell lysates or other biological fluids.

Human Protectin (CD59) ELISA Kit

RD-CD59-Hu-48Tests 48 Tests
EUR 500

Human Protectin (CD59) ELISA Kit

RD-CD59-Hu-96Tests 96 Tests
EUR 692

Human Protectin (CD59) ELISA Kit

RDR-CD59-Hu-48Tests 48 Tests
EUR 522

Human Protectin (CD59) ELISA Kit

RDR-CD59-Hu-96Tests 96 Tests
EUR 724

Mouse Monoclonal Anti-Human CD59, (Biotin) (Clone 1F5) (mouse IgG1)

CD59-B 25 tests
EUR 408

Mouse Monoclonal Anti-Human CD59, (FITC) (Clone 1F5) (mouse IgG1)

CD59-F 25 tests
EUR 408

Mouse Monoclonal Anti-Human CD59, (PE) (Clone 1F5) (mouse IgG1)

CD59-PE 25 tests
EUR 408

Protectin (CD59) Monoclonal Antibody (Rabbit)

4-MAB336Rb21
  • EUR 251.00
  • EUR 2589.00
  • EUR 643.00
  • EUR 317.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ser25~Leu104
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rabbit Protectin (CD59)

Protectin (CD59) Antibody

20-abx111491
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Protectin (CD59) Antibody

20-abx109633
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Protectin (CD59) Antibody

20-abx109634
  • EUR 411.00