Tag: western blot reagent

The SUMO-specific protease SENP2 plays an essential role in the regulation of Kv7.2 and Kv7.3 potassium channels

The SUMO-specific protease SENP2 plays an essential role in the regulation of Kv7.2 and Kv7.3 potassium channelsThe SUMO-specific protease SENP2 plays an essential role in the regulation of Kv7.2 and Kv7.3 potassium channels

SENP2 (Sentrin/SUMO-specific protease 2)-deficient mice develop spontaneous seizures in adolescence as a result of a marked discount in M-currents, which regulate neuronal membrane excitability. We now have beforehand proven that