Mammalian Cell-Free System Recapitulates the Early Events of Post-Fertilization Sperm Mitophagy

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Mammalian Cell-Free System Recapitulates the Early Occasions of Submit-Fertilization Sperm Mitophagy

Propagation of paternal sperm-contributed mitochondrial genes, leading to heteroplasmy, is seldom noticed in mammals attributable to post-fertilization degradation of sperm mitochondria, known as sperm mitophagy. Entire organelle sperm mitochondrion degradation is considered mediated by the interaction between the ubiquitin-proteasome system (UPS) and the autophagic pathway. Each porcine and primate post-fertilization sperm mitophagy depend on the ubiquitin-binding […]

Epitope Analysis of Anti-SARS-CoV-2 Neutralizing Antibodies

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Epitope Analysis of Anti-SARS-CoV-2 Neutralizing Antibodies

Coronavirus illness 2019 is threatening hundreds of tens of millions of individuals all over the world. Within the absence of particular and extremely efficient medicines, the therapy of contaminated individuals continues to be very difficult. As therapeutics, neutralizing antibodies (NAbs) have nice potential. Many NAbs have been reported, and most goal numerous areas on the […]