Mammalian Cell-Free System Recapitulates the Early Events of Post-Fertilization Sperm Mitophagy

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Mammalian Cell-Free System Recapitulates the Early Occasions of Put up-Fertilization Sperm Mitophagy

Propagation of paternal sperm-contributed mitochondrial genes, leading to heteroplasmy, is seldom noticed in mammals on account of post-fertilization degradation of sperm mitochondria, known as sperm mitophagy. Complete organelle sperm mitochondrion degradation is regarded as mediated by the interaction between the ubiquitin-proteasome system (UPS) and the autophagic pathway. Each porcine and primate post-fertilization sperm mitophagy depend […]