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Expression, purification, and biochemical characterization of an NAD +-dependent homoserine dehydrogenase from the symbiotic Polynucleobacter necessarius subsp. necessarius

Expression, purification, and biochemical characterization of an NAD +-dependent homoserine dehydrogenase from the symbiotic Polynucleobacter necessarius subsp. necessariusExpression, purification, and biochemical characterization of an NAD +-dependent homoserine dehydrogenase from the symbiotic Polynucleobacter necessarius subsp. necessarius

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Homoserine dehydrogenase (HSD), encoded by the hom gene, is a key enzyme within the aspartate pathway, which reversibly catalyzes the conversion of l-aspartate β-semialdehyde to l-homoserine (l-Hse), utilizing both NAD(H)

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